influenza-x

Astaxanthin therapeutic results by integrative evaluation of RNA

Identification of strong genetic signatures related to lipopolysaccharide-induced acute lung damage onset and astaxanthin therapeutic results by integrative evaluation of RNA sequencing information and GEO datasets

 

Acute lung damage (ALI) and acute respiratory misery syndrome (ARDS) are life-threatening scientific situations predominantly arising from uncontrolled inflammatory reactions. It has been discovered that the administration of astaxanthin (AST) can exert protecting results in opposition to lipopolysaccharide (LPS)-induced ALI; nevertheless, the strong genetic signatures underlying LPS induction and AST therapy stay obscure.

Right here we carried out a statistical meta-analysis of 5 publicly obtainable gene expression datasets from LPS-induced ALI mouse fashions, performed RNA-sequencing (RNA-seq) to display screen differentially expressed genes (DEGs) in response to LPS administration and AST therapy, and integrative evaluation to find out strong genetic signatures related to LPS-induced ALI onset and AST administration.

Each the meta-analyses and our experimental information recognized a complete of 198 DEGs in response to LPS administration, and 11 core DEGs (Timp1, Ly6i, Cxcl13, Irf7, Cxcl5, Ccl7, Isg15, Saa3, Saa1, Tgtp1, and Gbp11) had been recognized to be related to AST therapeutic results. Additional, the 11 core DEGs had been verified by quantitative real-time PCR (qRT-PCR) and immunohistochemistry (IHC), and purposeful enrichment evaluation revealed that these genes are primarily related to neutrophils and chemokines.

Collectively, these findings unearthed the strong genetic signatures underlying LPS administration and the molecular targets of AST for ameliorating ALI/ARDS which offer instructions for additional analysis.

influenza-x

influenza-x

Anti-Ephrin A3 (1C12)

YF-MA12782 100 ug
EUR 363
Description: Mouse monoclonal to Ephrin A3

Anti-Ephrin A3 (2H3)

YF-MA12783 100 ug
EUR 363
Description: Mouse monoclonal to Ephrin A3

Anti-EFNA3/Ephrin A3 Antibody

A07595 100ul
EUR 397
Description: Rabbit Polyclonal EFNA3/Ephrin A3 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Ephrin A3 Protein

20-abx261067
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Ephrin A3 antibody

70R-49686 100 ul
EUR 244
Description: Purified Polyclonal Ephrin A3 antibody

Recombinant Human Ephrin A3 Protein

RP01022 5 μg
EUR 136

Human Ephrin A3 (EFNA3) Protein

20-abx650580
  • EUR 676.00
  • EUR 286.00
  • EUR 2082.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Ephrin A3 (EFNA3)

4-RPE109Hu01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Ephrin A3 expressed in: E.coli

Ephrin-A3 Polyclonal Antibody

ES2277-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Ephrin-A3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Ephrin-A3 Polyclonal Antibody

ES2277-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Ephrin-A3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Ephrin A3 (EFNA3) Antibody

20-abx130988
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ephrin A3 (EFNA3) Antibody

20-abx112312
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Ephrin-A3 Polyclonal Antibody

ABP51278-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Ephrin-A3 from Human, Mouse, Rat. This Ephrin-A3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Ephrin-A3 at AA range: 130-210

Ephrin-A3 Polyclonal Antibody

ABP51278-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Ephrin-A3 from Human, Mouse, Rat. This Ephrin-A3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Ephrin-A3 at AA range: 130-210

Ephrin-A3 Polyclonal Antibody

ABP51278-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Ephrin-A3 from Human, Mouse, Rat. This Ephrin-A3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Ephrin-A3 at AA range: 130-210

Ephrin A3 (EFNA3) Antibody

20-abx320526
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Ephrin A3 (EFNA3) Antibody

20-abx321473
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Ephrin A3 Blocking Peptide

20-abx062561
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Ephrin A3 (EFNA3) Antibody

abx145187-100ug 100 ug
EUR 391

Ephrin A3 (EFNA3) Antibody

20-abx005870
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ephrin A3 (EFNA3) Antibody

20-abx009311
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Ephrin A3 (EFNA3) Antibody

20-abx013530
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ephrin A3 (EFNA3) Antibody

20-abx212623
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Ephrin A3 (EFNA3) Antibody

20-abx212624
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Ephrin A3 (EFNA3) Antibody

abx232808-100ug 100 ug
EUR 481

Ephrin A3 (EFNA3) Antibody

20-abx172261
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Ephrin A3 (EFNA3) Antibody

20-abx329235
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Ephrin A3 (EFNA3) Antibody

abx332529-100ul 100 ul
EUR 425

Ephrin A3 Recombinant Protein

96-249 0.2 mg
EUR 490.25
Description: Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

Ephrin-A3 Recombinant Protein

91-420 0.05 mg
EUR 311.75
Description: Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.

Ephrin A3 Recombinant Protein

92-586 0.05 mg
EUR 490.25
Description: Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human)

4-PAE109Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3)

Human Ephrin A3 (EFNA3) ELISA Kit

SEE109Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit

SEE109Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit

SEE109Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit

SEE109Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit

4-SEE109Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Ephrin A3 (EFNA3) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

EFNA3 Ephrin A3 Human Recombinant Protein

PROTP52797 Regular: 20ug
EUR 317
Description: EFNA3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 217 amino acids (23-214 a.a) and having a molecular mass of 24kDa. EFNA3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Ephrin A3 (EFNA3) ELISA Kit

RD-EFNA3-Hu-48Tests 48 Tests
EUR 521

Human Ephrin A3 (EFNA3) ELISA Kit

RD-EFNA3-Hu-96Tests 96 Tests
EUR 723

Human EFNA3/ Ephrin-A3 ELISA Kit

E0768Hu 1 Kit
EUR 571

Human Ephrin A3 (EFNA3) ELISA Kit

DLR-EFNA3-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Ephrin A3 (EFNA3) in samples from tissue homogenates or other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit

DLR-EFNA3-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Ephrin A3 (EFNA3) in samples from tissue homogenates or other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit

abx571238-96tests 96 tests
EUR 668

Human Ephrin A3 (EFNA3) CLIA Kit

20-abx494500
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Ephrin A3 (EFNA3) ELISA Kit

20-abx151428
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Ephrin A3 (EFNA3) CLIA Kit

abx196631-96tests 96 tests
EUR 825

Human Ephrin A3 (EFNA3) ELISA Kit

abx252367-96tests 96 tests
EUR 668

Human Ephrin A3 (EFNA3) ELISA Kit

RDR-EFNA3-Hu-48Tests 48 Tests
EUR 544

Human Ephrin A3 (EFNA3) ELISA Kit

RDR-EFNA3-Hu-96Tests 96 Tests
EUR 756

Human EFNA3(Ephrin A3) ELISA Kit

EH2978 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), APC

4-PAE109Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with APC.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), Biotinylated

4-PAE109Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with Biotin.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), Cy3

4-PAE109Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with Cy3.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), FITC

4-PAE109Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with FITC.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), HRP

4-PAE109Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with HRP.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), PE

4-PAE109Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with PE.

CLIA kit for Human EFNA3 (Ephrin A3)

E-CL-H0716 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human EFNA3 (Ephrin A3) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Ephrin-A3 (EFNA3)

KTE61948-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human Ephrin-A3 (EFNA3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Ephrin-A3 (EFNA3)

KTE61948-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Ephrin-A3 (EFNA3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Ephrin-A3 (EFNA3)

KTE61948-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human Ephrin-A3 (EFNA3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human EFNA3 (Ephrin A3)

E-EL-H1067 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Human EFNA3 (Ephrin A3) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human EFNA3 (Ephrin A3)

ELK3830 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Ephrin A3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Recombinant Human Ephrin-A3/EFNA3(C-6His)

C464-10ug 10ug
EUR 80
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Ephrin-A3/EFNA3(C-6His)

C464-1mg 1mg
EUR 608
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Ephrin-A3/EFNA3(C-6His)

C464-500ug 500ug
EUR 461
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Ephrin-A3/EFNA3(C-6His)

C464-50ug 50ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Rabbit Ephrin A3 (EFNA3) ELISA Kit

abx363749-96tests 96 tests
EUR 825

Pig Ephrin A3 (EFNA3) ELISA Kit

abx360594-96tests 96 tests
EUR 825

Chicken Ephrin A3 (EFNA3) ELISA Kit

abx355668-96tests 96 tests
EUR 825

Monkey Ephrin A3 (EFNA3) ELISA Kit

abx358709-96tests 96 tests
EUR 825

Mouse Ephrin A3 (EFNA3) ELISA Kit

abx512529-96tests 96 tests
EUR 668

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), APC-Cy7

4-PAE109Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with APC-Cy7.

Guinea pig Ephrin A3 (EFNA3) ELISA Kit

abx358173-96tests 96 tests
EUR 825

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)

CK92-10ug 10ug
EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)

CK92-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)

CK92-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)

CK92-50ug 50ug
EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

anti-Ephrin A1

YF-PA11501 100 ug
EUR 403
Description: Rabbit polyclonal to Ephrin A1

anti-Ephrin A2

YF-PA11502 50 ul
EUR 363
Description: Mouse polyclonal to Ephrin A2

anti-Ephrin A2

YF-PA11503 50 ug
EUR 363
Description: Mouse polyclonal to Ephrin A2

anti-Ephrin A5

YF-PA23626 50 ul
EUR 334
Description: Mouse polyclonal to Ephrin A5

anti-Ephrin B2

YF-PA23627 50 ul
EUR 334
Description: Mouse polyclonal to Ephrin B2

anti-Annexin A3

YF-PA10220 50 ug
EUR 363
Description: Mouse polyclonal to Annexin A3

anti-Annexin A3

YF-PA10221 100 ug
EUR 403
Description: Rabbit polyclonal to Annexin A3

anti-Plexin A3

YF-PA26342 50 ul
EUR 334
Description: Mouse polyclonal to Plexin A3

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [Fc]

VAng-1502Lsx-1mg 1 mg
EUR 2470
Description: Human Ephrin-A3 (EFNA3), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [Fc]

VAng-1502Lsx-200g 200 µg
EUR 738
Description: Human Ephrin-A3 (EFNA3), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [His]

VAng-1503Lsx-1mg 1 mg
EUR 2470
Description: Human Ephrin-A3 (EFNA3), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [His]

VAng-1503Lsx-200g 200 µg
EUR 738
Description: Human Ephrin-A3 (EFNA3), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

ES 8/10 Double Gel Comb For ES Electrophoresis

LE1011-A3 Ea
EUR 124

Anti-Ephrin-B3 Antibody

A04098 100ul
EUR 397
Description: Rabbit Polyclonal Ephrin-B3 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Ephrin-A4 Antibody

A09230 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Ephrin-A4 Antibody (EFNA4) detection. Tested with WB in Human, Mouse.

 

 

Lengthy non-coding RNAs in motor neuron growth and illness

 

Lengthy non-coding RNAs (lncRNAs) are RNAs that exceed 200 nucleotides in size and that aren’t translated into proteins. 1000’s of lncRNAs have been recognized with features in processes akin to transcription and translation regulation, RNA processing, and RNA and protein sponging. LncRNAs present outstanding expression within the nervous system and have been implicated in neural growth, perform and illness.

Current work has begun to report on the expression and roles of lncRNAs in motor neurons (MNs). The cell our bodies of MNs are situated in cortex, brainstem or spinal wire and their axons undertaking into the brainstem, spinal wire or in direction of peripheral muscle tissues, thereby controlling essential features akin to motion, respiration and swallowing.

Degeneration of MNs is a pathological hallmark of ailments akin to amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). LncRNAs affect a number of elements of MN growth and disruptions in these lncRNA-mediated results are proposed to contribute to the pathogenic mechanisms underlying MN illness (MND).

Accumulating proof means that lncRNAs might comprise invaluable therapeutic targets for various MNDs. On this overview, we talk about the function of lncRNAs (together with round RNAs (circRNAs)) within the growth of MNs, talk about how lncRNAs might contribute to MNDs and supply instructions for future analysis.

Function of DNA methylation and CpG websites within the viral telomerase RNA promoter throughout Gallid herpesvirus 2 pathogenesis

 

  • Gallid herpesvirus kind 2 (GaHV-2) is an oncogenic alphaherpesvirus that induces malignant T-cell lymphoma in rooster. GaHV-2 encodes a viral telomerase RNA subunit (vTR) that performs a vital function in virus-induced tumorigenesis, enhances telomerase exercise and possesses perform unbiased of the telomerase advanced. vTR is pushed by a strong viral promoter, extremely expressed in virus-infected cells and controlled by two c-Myc response components (c-Myc REs). The regulatory mechanisms concerned in controlling vTR and different genes throughout viral replication and latency stay poorly understood however are essential to know this oncogenic herpesvirus.

 

  • Due to this fact, we investigated DNA methylation patterns of CpG dinucleotides discovered within the vTR promoter and measured the affect of methylation on the telomerase exercise. We demonstrated that telomerase exercise was significantly elevated following viral reactivation.
  • Moreover, CpG websites inside c-Myc REs confirmed particular modifications in methylation after in vitroreactivation and in contaminated animals over time. Promoter reporter assays indicated that one of many c-Myc RE is concerned in regulating vTR transcription, and that methylation strongly influenced vTR promoter exercise.

 

 

  • To review the significance of the CpG websites present in c-Myc REs in virus-induced tumorigenesis, we generated a recombinant virus containing mutations in each CpG websites of c-Myc REs in addition to revertant, by two-step Pink-mediated mutagenesis.
  • Launched mutation in vTR promoter didn’t have an effect on the replication properties of the recombinant viruses in vitroIn distinction, replication of the mutant virus in contaminated chickens was severely impaired, and tumour formation utterly Our information supplied a extra in-depth characterisation of c-Myc oncoprotein REs and DNA methylation involvement in transcriptional regulation of vTR.

 

  • IMPORTANCEEarlier research demonstrated that telomerase RNAs possess features that promote tumour growth unbiased of the telomerase advanced. vTR is a herpesvirus-encoded telomerase RNA subunit that performs a vital function in virus-induced tumorigenesis and is expressed by a strong viral promoter that’s extremely regulated by the c-Myc oncoprotein binding to the E-boxes.

 

 

  • Right here we demonstrated that the DNA methylation patterns within the purposeful c-Myc response components of the vTR promoter change upon reactivation from latency and that demethylation strongly will increase telomerase exercise in virus-infected cells. Furthermore, the introduction of mutation within the CpG dinucleotides of the c-Myc binding websites resulted in decreased vTR expression and full abrogation of tumour formation. Our research offers additional affirmation of the involvement of particular DNA methylation patterns within the regulation of vTR expression and vTR significance for virus-induced tumorigenesis.

 

Anti-Angiogenin/ANG Antibody

A00146 100ug/vial
EUR 294

Mouse Anti Human Angiogenin Monoclonal Antibody

CABT-49293MH 0.15 mg
EUR 1053

Angiogenin

PR27204 5 ug
EUR 191

Human Angiogenin (ANG)

1-CSB-RP057294h
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Angiogenin(ANG),partial expressed in E.coli

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Angiogenin Protein

20-abx261289
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Angiogenin antibody

70R-15437 100 ug
EUR 327
Description: Rabbit polyclonal Angiogenin antibody

Angiogenin Human Recombinant Protein

PROTP03950 Regular: 20ug
EUR 317
Description: ANG Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (25-147) and having a molecular mass of 16.4 kDa.;ANG is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Human Angiogenin (ANG) Protein

20-abx166508
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Angiogenin (ANG) Antibody

31388-05111 150 ug
EUR 261

Human Angiogenin ELISA kit

E01A0501-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Angiogenin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiogenin ELISA kit

E01A0501-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Angiogenin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiogenin ELISA kit

E01A0501-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Angiogenin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiogenin ELISA kit

55R-2081 96 tests
EUR 712
Description: ELISA Kit for detection of Angiogenin in the research laboratory

Angiogenin (108-122)

HY-P1516 10mg
EUR 980

Angiogenin (ANG) Antibody

20-abx132357
  • EUR 328.00
  • EUR 829.00
  • EUR 425.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx128903
  • EUR 314.00
  • EUR 133.00
  • EUR 829.00
  • EUR 439.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx129495
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx121013
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Angiogenin (ANG) Antibody

20-abx110971
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Angiogenin (ANG) Antibody

20-abx109530
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx100298
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx100299
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx100300
  • EUR 453.00
  • EUR 133.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx100301
  • EUR 453.00
  • EUR 133.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx100302
  • EUR 356.00
  • EUR 913.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiogenin (ANG) Antibody

20-abx001302
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Angiogenin (108-122)

5-00673 4 x 1mg Ask for price

Angiogenin (108-123)

5-00674 4 x 1mg Ask for price

Angiogenin (ANG) Antibody

20-abx171213
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Angiogenin (ANG) Antibody

20-abx323491
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Angiogenin (ANG) Antibody

abx230390-100ug 100 ug
EUR 481

Angiogenin (ANG) Antibody

20-abx339590
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Angiogenin (ANG) Antibody

abx148162-100ug 100 ug
EUR 439

Angiogenin (ANG) Antibody

20-abx141176
  • EUR 356.00
  • EUR 537.00
  • EUR 217.00
  • 100 ul
  • 200 ul
  • 30 ul

Angiogenin (ANG) Antibody

20-abx175378
  • EUR 1316.00
  • EUR 634.00
  • 1 mg
  • 200 ug

Angiogenin Polyclonal Antibody

42438-100ul 100ul
EUR 333

Recombinant Angiogenin (ANG)

4-RPA007Bo01
  • EUR 504.99
  • EUR 238.00
  • EUR 1618.72
  • EUR 606.24
  • EUR 1112.48
  • EUR 401.00
  • EUR 3896.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Bovine Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)

4-RPA007Hu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)

4-RPA007Mu01
  • EUR 478.11
  • EUR 231.00
  • EUR 1517.92
  • EUR 572.64
  • EUR 1045.28
  • EUR 383.00
  • EUR 3644.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)

4-RPA007Mu02
  • EUR 478.11
  • EUR 231.00
  • EUR 1517.92
  • EUR 572.64
  • EUR 1045.28
  • EUR 383.00
  • EUR 3644.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)

4-RPA007Po01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)

4-RPA007Ra01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Angiogenin expressed in: E.coli

Angiogenin (108-123)

H-8020.0001 1.0mg
EUR 441
Description: Sum Formula: C83H132N26O24; CAS# [112173-48-5]

Angiogenin (108-123)

H-8020.0005 5.0mg
EUR 1675
Description: Sum Formula: C83H132N26O24; CAS# [112173-48-5]

Angiogenin (108-122)

H-8095.0001 1.0mg
EUR 212
Description: Sum Formula: C78H125N25O23; CAS# [112173-49-6]

Angiogenin (108-122)

H-8095.0005 5.0mg
EUR 756
Description: Sum Formula: C78H125N25O23; CAS# [112173-49-6]

Angiogenin antibody (HRP)

60R-2121 100 ug
EUR 327
Description: Rabbit polyclonal Angiogenin antibody (HRP)

Angiogenin antibody (FITC)

60R-2122 100 ug
EUR 327
Description: Rabbit polyclonal Angiogenin antibody (FITC)

Angiogenin antibody (biotin)

60R-2123 100 ug
EUR 349
Description: Rabbit polyclonal Angiogenin antibody (biotin)

Angiogenin Recombinant Protein

91-183 0.05 mg
EUR 464
Description: Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.

Human Angiogenin(ANG)ELISA Kit

GA-E1240HM-48T 48T
EUR 289

Human Angiogenin(ANG)ELISA Kit

GA-E1240HM-96T 96T
EUR 466

Human ANG/ Angiogenin ELISA Kit

E0142Hu 1 Kit
EUR 537

Human Angiogenin,ANG ELISA Kit

201-12-1224 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Angiogenin (ANG) CLIA Kit

20-abx490752
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Angiogenin (ANG) ELISA Kit

abx350014-96tests 96 tests
EUR 668

Human Angiogenin (ANG) ELISA Kit

20-abx150645
  • EUR 5640.00
  • EUR 3009.00
  • EUR 707.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Angiogenin (ANG) CLIA Kit

abx195094-96tests 96 tests
EUR 825

Human Angiogenin (ANG) ELISA Kit

RDR-RNASE5-Hu-48Tests 48 Tests
EUR 383

Human Angiogenin (ANG) ELISA Kit

RDR-RNASE5-Hu-96Tests 96 Tests
EUR 525

Human Angiogenin (ANG) ELISA Kit

RD-RNASE5-Hu-48Tests 48 Tests
EUR 367

Human Angiogenin (ANG) ELISA Kit

RD-RNASE5-Hu-96Tests 96 Tests
EUR 502

Human Angiogenin ELISA Kit (ANG)

RK00879 96 Tests
EUR 521

ELISA kit for Human Angiogenin

EK1015 96 tests
EUR 452
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Angiogenin in samples from serum, plasma, tissue homogenates and other biological fluids.

Human ANG(Angiogenin) ELISA Kit

EH0034 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human Angiogenin (ANG) ELISA Kit

DLR-RNASE5-Hu-48T 48T
EUR 380
Description: A sandwich quantitative ELISA assay kit for detection of Human Angiogenin (ANG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Angiogenin (ANG) ELISA Kit

DLR-RNASE5-Hu-96T 96T
EUR 485
Description: A sandwich quantitative ELISA assay kit for detection of Human Angiogenin (ANG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Angiogenin (ANG) Polyclonal Antibody (Human)

4-PAA007Hu01
  • EUR 194.00
  • EUR 1678.00
  • EUR 436.00
  • EUR 234.00
  • EUR 191.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Angiogenin (ANG)

Human Angiogenin, ANG ELISA Kit

CSB-E04498h-24T 1 plate of 24 wells
EUR 165
Description: Quantitative sandwich ELISA kit for measuring Human Angiogenin, ANG in samples from serum, plasma, cell culture supernates, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Angiogenin, ANG ELISA Kit

1-CSB-E04498h
  • EUR 511.00
  • EUR 3491.00
  • EUR 1866.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Angiogenin, ANG in samples from serum, plasma, cell culture supernates, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Angiogenin (ANG) Monoclonal Antibody (Human)

4-MAA007Hu22
  • EUR 249.00
  • EUR 2549.00
  • EUR 634.00
  • EUR 313.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Angiogenin (ANG)

Human Angiogenin (ANG) ELISA Kit

SEA007Hu-10x96wellstestplate 10x96-wells test plate
EUR 3409.41
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit

SEA007Hu-1x48wellstestplate 1x48-wells test plate
EUR 368.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit

SEA007Hu-1x96wellstestplate 1x96-wells test plate
EUR 483.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit

SEA007Hu-5x96wellstestplate 5x96-wells test plate
EUR 1875.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit

4-SEA007Hu
  • EUR 3460.00
  • EUR 1826.00
  • EUR 484.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Angiogenin (ANG) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Angiogenin(ANG)ELISA Kit

QY-E00700 96T
EUR 361

Recombinant Human Angiogenin/ANG/RNASE5

C203-10ug 10ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Angiogenin/ANG/RNASE5

C203-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Angiogenin/ANG/RNASE5

C203-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Angiogenin/ANG/RNASE5

C203-50ug 50ug
EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Human ANG / Angiogenin ELISA kit

LF-EK50621 1×96T
EUR 648

Human Angiogenin,ANG ELISA Kit

CN-03157H1 96T
EUR 378

Human Angiogenin,ANG ELISA Kit

CN-03157H2 48T
EUR 289

Goat Anti-Human Angiogenin protein IgG #1, IgG aff pure

ANGN12-A 100 ug
EUR 482

ELISA kit for Human ANG (Angiogenin)

ELK1830 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Angiogenin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.