Identification of strong genetic signatures related to lipopolysaccharide-induced acute lung damage onset and astaxanthin therapeutic results by integrative evaluation of RNA sequencing information and GEO datasets

 

Acute lung damage (ALI) and acute respiratory misery syndrome (ARDS) are life-threatening scientific situations predominantly arising from uncontrolled inflammatory reactions. It has been discovered that the administration of astaxanthin (AST) can exert protecting results in opposition to lipopolysaccharide (LPS)-induced ALI; nevertheless, the strong genetic signatures underlying LPS induction and AST therapy stay obscure.

Right here we carried out a statistical meta-analysis of 5 publicly obtainable gene expression datasets from LPS-induced ALI mouse fashions, performed RNA-sequencing (RNA-seq) to display screen differentially expressed genes (DEGs) in response to LPS administration and AST therapy, and integrative evaluation to find out strong genetic signatures related to LPS-induced ALI onset and AST administration.

Each the meta-analyses and our experimental information recognized a complete of 198 DEGs in response to LPS administration, and 11 core DEGs (Timp1, Ly6i, Cxcl13, Irf7, Cxcl5, Ccl7, Isg15, Saa3, Saa1, Tgtp1, and Gbp11) had been recognized to be related to AST therapeutic results. Additional, the 11 core DEGs had been verified by quantitative real-time PCR (qRT-PCR) and immunohistochemistry (IHC), and purposeful enrichment evaluation revealed that these genes are primarily related to neutrophils and chemokines.

Collectively, these findings unearthed the strong genetic signatures underlying LPS administration and the molecular targets of AST for ameliorating ALI/ARDS which offer instructions for additional analysis.

Anti-Ephrin A3 (1C12)
YF-MA12782	Abfrontier	100 ug	EUR 363
Description: Mouse monoclonal to Ephrin A3

Anti-Ephrin A3 (2H3)
YF-MA12783	Abfrontier	100 ug	EUR 363
Description: Mouse monoclonal to Ephrin A3

Anti-EFNA3/Ephrin A3 Antibody
A07595	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal EFNA3/Ephrin A3 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Ephrin A3 Protein
20-abx261067	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug

Ephrin A3 antibody
70R-49686	Fitzgerald	100 ul	EUR 244
Description: Purified Polyclonal Ephrin A3 antibody

Recombinant Human Ephrin A3 Protein
RP01022	Abclonal	5 μg	EUR 136

Human Ephrin A3 (EFNA3) Protein
20-abx650580	Abbexa	EUR 676.00 EUR 286.00 EUR 2082.00 EUR 801.00 EUR 481.00	100 ug 10 ug 1 mg 200 ug 50 ug

Recombinant Ephrin A3 (EFNA3)
4-RPE109Hu01	Cloud-Clone	EUR 485.28 EUR 233.00 EUR 1544.80 EUR 581.60 EUR 1063.20 EUR 388.00 EUR 3712.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Ephrin A3 expressed in: E.coli

Ephrin-A3 Polyclonal Antibody
ES2277-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against Ephrin-A3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Ephrin-A3 Polyclonal Antibody
ES2277-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against Ephrin-A3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Ephrin A3 (EFNA3) Antibody
20-abx130988	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Ephrin A3 (EFNA3) Antibody
20-abx112312	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Ephrin-A3 Polyclonal Antibody
ABP51278-003ml	Abbkine	0.03ml	EUR 158
Description: A polyclonal antibody for detection of Ephrin-A3 from Human, Mouse, Rat. This Ephrin-A3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Ephrin-A3 at AA range: 130-210

Ephrin-A3 Polyclonal Antibody
ABP51278-01ml	Abbkine	0.1ml	EUR 289
Description: A polyclonal antibody for detection of Ephrin-A3 from Human, Mouse, Rat. This Ephrin-A3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Ephrin-A3 at AA range: 130-210

Ephrin-A3 Polyclonal Antibody
ABP51278-02ml	Abbkine	0.2ml	EUR 414
Description: A polyclonal antibody for detection of Ephrin-A3 from Human, Mouse, Rat. This Ephrin-A3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Ephrin-A3 at AA range: 130-210

Ephrin A3 (EFNA3) Antibody
20-abx320526	Abbexa	EUR 300.00 EUR 244.00	100 ul 50 ul

Ephrin A3 (EFNA3) Antibody
20-abx321473	Abbexa	EUR 300.00 EUR 244.00	100 ul 50 ul

Ephrin A3 Blocking Peptide
20-abx062561	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg

Ephrin A3 (EFNA3) Antibody
abx145187-100ug	Abbexa	100 ug	EUR 391

Ephrin A3 (EFNA3) Antibody
20-abx005870	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Ephrin A3 (EFNA3) Antibody
20-abx009311	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Ephrin A3 (EFNA3) Antibody
20-abx013530	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Ephrin A3 (EFNA3) Antibody
20-abx212623	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Ephrin A3 (EFNA3) Antibody
20-abx212624	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Ephrin A3 (EFNA3) Antibody
abx232808-100ug	Abbexa	100 ug	EUR 481

Ephrin A3 (EFNA3) Antibody
20-abx172261	Abbexa	EUR 857.00 EUR 439.00	1 mg 200 ug

Ephrin A3 (EFNA3) Antibody
20-abx329235	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Ephrin A3 (EFNA3) Antibody
abx332529-100ul	Abbexa	100 ul	EUR 425

Ephrin A3 Recombinant Protein
96-249	ProSci	0.2 mg	EUR 490.25
Description: Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

Ephrin-A3 Recombinant Protein
91-420	ProSci	0.05 mg	EUR 311.75
Description: Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.

Ephrin A3 Recombinant Protein
92-586	ProSci	0.05 mg	EUR 490.25
Description: Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human)
4-PAE109Hu01	Cloud-Clone	EUR 247.00 EUR 2510.00 EUR 625.00 EUR 310.00 EUR 214.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3)

Human Ephrin A3 (EFNA3) ELISA Kit
SEE109Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit
SEE109Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit
SEE109Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit
SEE109Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Ephrin A3 (EFNA3) in Tissue homogenates and other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit
4-SEE109Hu	Cloud-Clone	EUR 4782.00 EUR 2526.00 EUR 640.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Ephrin A3 (EFNA3) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

EFNA3 Ephrin A3 Human Recombinant Protein
PROTP52797	BosterBio	Regular: 20ug	EUR 317
Description: EFNA3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 217 amino acids (23-214 a.a) and having a molecular mass of 24kDa. EFNA3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Ephrin A3 (EFNA3) ELISA Kit
RD-EFNA3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 521

Human Ephrin A3 (EFNA3) ELISA Kit
RD-EFNA3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 723

Human EFNA3/ Ephrin-A3 ELISA Kit
E0768Hu	Sunlong	1 Kit	EUR 571

Human Ephrin A3 (EFNA3) ELISA Kit
DLR-EFNA3-Hu-48T	DL Develop	48T	EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Ephrin A3 (EFNA3) in samples from tissue homogenates or other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit
DLR-EFNA3-Hu-96T	DL Develop	96T	EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Ephrin A3 (EFNA3) in samples from tissue homogenates or other biological fluids.

Human Ephrin A3 (EFNA3) ELISA Kit
abx571238-96tests	Abbexa	96 tests	EUR 668

Human Ephrin A3 (EFNA3) CLIA Kit
20-abx494500	Abbexa	EUR 7973.00 EUR 4246.00 EUR 981.00	10 × 96 tests 5 × 96 tests 96 tests

Human Ephrin A3 (EFNA3) ELISA Kit
20-abx151428	Abbexa	EUR 7378.00 EUR 3933.00 EUR 911.00	10 × 96 tests 5 × 96 tests 96 tests

Human Ephrin A3 (EFNA3) CLIA Kit
abx196631-96tests	Abbexa	96 tests	EUR 825

Human Ephrin A3 (EFNA3) ELISA Kit
abx252367-96tests	Abbexa	96 tests	EUR 668

Human Ephrin A3 (EFNA3) ELISA Kit
RDR-EFNA3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 544

Human Ephrin A3 (EFNA3) ELISA Kit
RDR-EFNA3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 756

Human EFNA3(Ephrin A3) ELISA Kit
EH2978	FN Test	96T	EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), APC
4-PAE109Hu01-APC	Cloud-Clone	EUR 345.00 EUR 3275.00 EUR 912.00 EUR 440.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with APC.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), Biotinylated
4-PAE109Hu01-Biotin	Cloud-Clone	EUR 311.00 EUR 2460.00 EUR 727.00 EUR 381.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with Biotin.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), Cy3
4-PAE109Hu01-Cy3	Cloud-Clone	EUR 419.00 EUR 4325.00 EUR 1175.00 EUR 545.00 EUR 251.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with Cy3.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), FITC
4-PAE109Hu01-FITC	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with FITC.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), HRP
4-PAE109Hu01-HRP	Cloud-Clone	EUR 316.00 EUR 2855.00 EUR 807.00 EUR 398.00 EUR 206.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with HRP.

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), PE
4-PAE109Hu01-PE	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with PE.

CLIA kit for Human EFNA3 (Ephrin A3)
E-CL-H0716	Elabscience Biotech	1 plate of 96 wells	EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human EFNA3 (Ephrin A3) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Ephrin-A3 (EFNA3)
KTE61948-48T	Abbkine	48T	EUR 332
Description: Quantitative sandwich ELISA for measuring Human Ephrin-A3 (EFNA3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Ephrin-A3 (EFNA3)
KTE61948-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Ephrin-A3 (EFNA3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Ephrin-A3 (EFNA3)
KTE61948-96T	Abbkine	96T	EUR 539
Description: Quantitative sandwich ELISA for measuring Human Ephrin-A3 (EFNA3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human EFNA3 (Ephrin A3)
E-EL-H1067	Elabscience Biotech	1 plate of 96 wells	EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Human EFNA3 (Ephrin A3) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human EFNA3 (Ephrin A3)
ELK3830	ELK Biotech	1 plate of 96 wells	EUR 432
Description: A sandwich ELISA kit for detection of Ephrin A3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Recombinant Human Ephrin-A3/EFNA3(C-6His)
C464-10ug	Novoprotein	10ug	EUR 80
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Ephrin-A3/EFNA3(C-6His)
C464-1mg	Novoprotein	1mg	EUR 608
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Ephrin-A3/EFNA3(C-6His)
C464-500ug	Novoprotein	500ug	EUR 461
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Ephrin-A3/EFNA3(C-6His)
C464-50ug	Novoprotein	50ug	EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Rabbit Ephrin A3 (EFNA3) ELISA Kit
abx363749-96tests	Abbexa	96 tests	EUR 825

Pig Ephrin A3 (EFNA3) ELISA Kit
abx360594-96tests	Abbexa	96 tests	EUR 825

Chicken Ephrin A3 (EFNA3) ELISA Kit
abx355668-96tests	Abbexa	96 tests	EUR 825

Monkey Ephrin A3 (EFNA3) ELISA Kit
abx358709-96tests	Abbexa	96 tests	EUR 825

Mouse Ephrin A3 (EFNA3) ELISA Kit
abx512529-96tests	Abbexa	96 tests	EUR 668

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	EUR 349

Ephrin A3 (EFNA3) Polyclonal Antibody (Human), APC-Cy7
4-PAE109Hu01-APC-Cy7	Cloud-Clone	EUR 571.00 EUR 6430.00 EUR 1705.00 EUR 760.00 EUR 319.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Ephrin A3 (EFNA3). This antibody is labeled with APC-Cy7.

Guinea pig Ephrin A3 (EFNA3) ELISA Kit
abx358173-96tests	Abbexa	96 tests	EUR 825

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)
CK92-10ug	Novoprotein	10ug	EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)
CK92-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)
CK92-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Mouse Ephrin-A3/EFNA3 (C-Fc)
CK92-50ug	Novoprotein	50ug	EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

anti-Ephrin A1
YF-PA11501	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to Ephrin A1

anti-Ephrin A2
YF-PA11502	Abfrontier	50 ul	EUR 363
Description: Mouse polyclonal to Ephrin A2

anti-Ephrin A2
YF-PA11503	Abfrontier	50 ug	EUR 363
Description: Mouse polyclonal to Ephrin A2

anti-Ephrin A5
YF-PA23626	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Ephrin A5

anti-Ephrin B2
YF-PA23627	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Ephrin B2

anti-Annexin A3
YF-PA10220	Abfrontier	50 ug	EUR 363
Description: Mouse polyclonal to Annexin A3

anti-Annexin A3
YF-PA10221	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to Annexin A3

anti-Plexin A3
YF-PA26342	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Plexin A3

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [Fc]
VAng-1502Lsx-1mg	Creative Biolabs	1 mg	EUR 2470
Description: Human Ephrin-A3 (EFNA3), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [Fc]
VAng-1502Lsx-200g	Creative Biolabs	200 µg	EUR 738
Description: Human Ephrin-A3 (EFNA3), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [His]
VAng-1503Lsx-1mg	Creative Biolabs	1 mg	EUR 2470
Description: Human Ephrin-A3 (EFNA3), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

Recombinant Ephrin-A3 Protein (Gln 23-Ser 213) [His]
VAng-1503Lsx-200g	Creative Biolabs	200 µg	EUR 738
Description: Human Ephrin-A3 (EFNA3), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAI10407)

ES 8/10 Double Gel Comb For ES Electrophoresis
LE1011-A3	GenDepot	Ea	EUR 124

Anti-Ephrin-B3 Antibody
A04098	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Ephrin-B3 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Ephrin-A4 Antibody
A09230	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Antibody for Ephrin-A4 Antibody (EFNA4) detection. Tested with WB in Human, Mouse.

 

 

Lengthy non-coding RNAs in motor neuron growth and illness

 

Lengthy non-coding RNAs (lncRNAs) are RNAs that exceed 200 nucleotides in size and that aren’t translated into proteins. 1000’s of lncRNAs have been recognized with features in processes akin to transcription and translation regulation, RNA processing, and RNA and protein sponging. LncRNAs present outstanding expression within the nervous system and have been implicated in neural growth, perform and illness.

Current work has begun to report on the expression and roles of lncRNAs in motor neurons (MNs). The cell our bodies of MNs are situated in cortex, brainstem or spinal wire and their axons undertaking into the brainstem, spinal wire or in direction of peripheral muscle tissues, thereby controlling essential features akin to motion, respiration and swallowing.

Degeneration of MNs is a pathological hallmark of ailments akin to amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). LncRNAs affect a number of elements of MN growth and disruptions in these lncRNA-mediated results are proposed to contribute to the pathogenic mechanisms underlying MN illness (MND).

Accumulating proof means that lncRNAs might comprise invaluable therapeutic targets for various MNDs. On this overview, we talk about the function of lncRNAs (together with round RNAs (circRNAs)) within the growth of MNs, talk about how lncRNAs might contribute to MNDs and supply instructions for future analysis.

Function of DNA methylation and CpG websites within the viral telomerase RNA promoter throughout Gallid herpesvirus 2 pathogenesis

 

• Gallid herpesvirus kind 2 (GaHV-2) is an oncogenic alphaherpesvirus that induces malignant T-cell lymphoma in rooster. GaHV-2 encodes a viral telomerase RNA subunit (vTR) that performs a vital function in virus-induced tumorigenesis, enhances telomerase exercise and possesses perform unbiased of the telomerase advanced. vTR is pushed by a strong viral promoter, extremely expressed in virus-infected cells and controlled by two c-Myc response components (c-Myc REs). The regulatory mechanisms concerned in controlling vTR and different genes throughout viral replication and latency stay poorly understood however are essential to know this oncogenic herpesvirus.

 

• Due to this fact, we investigated DNA methylation patterns of CpG dinucleotides discovered within the vTR promoter and measured the affect of methylation on the telomerase exercise. We demonstrated that telomerase exercise was significantly elevated following viral reactivation.
• Moreover, CpG websites inside c-Myc REs confirmed particular modifications in methylation after in vitroreactivation and in contaminated animals over time. Promoter reporter assays indicated that one of many c-Myc RE is concerned in regulating vTR transcription, and that methylation strongly influenced vTR promoter exercise.

 

 

• To review the significance of the CpG websites present in c-Myc REs in virus-induced tumorigenesis, we generated a recombinant virus containing mutations in each CpG websites of c-Myc REs in addition to revertant, by two-step Pink-mediated mutagenesis.
• Launched mutation in vTR promoter didn’t have an effect on the replication properties of the recombinant viruses in vitroIn distinction, replication of the mutant virus in contaminated chickens was severely impaired, and tumour formation utterly Our information supplied a extra in-depth characterisation of c-Myc oncoprotein REs and DNA methylation involvement in transcriptional regulation of vTR.

 

• IMPORTANCEEarlier research demonstrated that telomerase RNAs possess features that promote tumour growth unbiased of the telomerase advanced. vTR is a herpesvirus-encoded telomerase RNA subunit that performs a vital function in virus-induced tumorigenesis and is expressed by a strong viral promoter that’s extremely regulated by the c-Myc oncoprotein binding to the E-boxes.

 

 

• Right here we demonstrated that the DNA methylation patterns within the purposeful c-Myc response components of the vTR promoter change upon reactivation from latency and that demethylation strongly will increase telomerase exercise in virus-infected cells. Furthermore, the introduction of mutation within the CpG dinucleotides of the c-Myc binding websites resulted in decreased vTR expression and full abrogation of tumour formation. Our research offers additional affirmation of the involvement of particular DNA methylation patterns within the regulation of vTR expression and vTR significance for virus-induced tumorigenesis.

 

Anti-Angiogenin/ANG Antibody
A00146	BosterBio	100ug/vial	EUR 294

Mouse Anti Human Angiogenin Monoclonal Antibody
CABT-49293MH	Creative Diagnostics	0.15 mg	EUR 1053

Angiogenin
PR27204	Neuromics	5 ug	EUR 191

Human Angiogenin (ANG)
1-CSB-RP057294h	Cusabio	EUR 380.00 EUR 214.00 EUR 1309.00 EUR 560.00 EUR 873.00 EUR 262.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Angiogenin(ANG),partial expressed in E.coli

Polyclonal Goat anti-GST α-form
GST-ANTI-1	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3	Detroit R&D	50 uL	EUR 280

Angiogenin Protein
20-abx261289	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug

Angiogenin antibody
70R-15437	Fitzgerald	100 ug	EUR 327
Description: Rabbit polyclonal Angiogenin antibody

Angiogenin Human Recombinant Protein
PROTP03950	BosterBio	Regular: 20ug	EUR 317
Description: ANG Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (25-147) and having a molecular mass of 16.4 kDa.;ANG is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Human Angiogenin (ANG) Protein
20-abx166508	Abbexa	EUR 648.00 EUR 272.00 EUR 1943.00 EUR 759.00 EUR 467.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Angiogenin (ANG) Antibody
31388-05111	AssayPro	150 ug	EUR 261

Human Angiogenin ELISA kit
E01A0501-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Angiogenin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiogenin ELISA kit
E01A0501-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Human Angiogenin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiogenin ELISA kit
E01A0501-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Human Angiogenin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiogenin ELISA kit
55R-2081	Fitzgerald	96 tests	EUR 712
Description: ELISA Kit for detection of Angiogenin in the research laboratory

Angiogenin (108-122)
HY-P1516	MedChemExpress	10mg	EUR 980

Angiogenin (ANG) Antibody
20-abx132357	Abbexa	EUR 328.00 EUR 829.00 EUR 425.00 EUR 154.00 EUR 258.00	100 ug 1 mg 200 ug 20 ug 50 ug

Angiogenin (ANG) Antibody
20-abx128903	Abbexa	EUR 314.00 EUR 133.00 EUR 829.00 EUR 439.00 EUR 272.00	100 ug 10 ug 1 mg 200 ug 50 ug

Angiogenin (ANG) Antibody
20-abx129495	Abbexa	EUR 411.00 EUR 133.00 EUR 1135.00 EUR 551.00 EUR 314.00	100 ug 10 ug 1 mg 200 ug 50 ug

Angiogenin (ANG) Antibody
20-abx121013	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Angiogenin (ANG) Antibody
20-abx110971	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Angiogenin (ANG) Antibody
20-abx109530	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Angiogenin (ANG) Antibody
20-abx100298	Abbexa	EUR 411.00 EUR 133.00 EUR 1135.00 EUR 551.00 EUR 314.00	100 ug 10 ug 1 mg 200 ug 50 ug

Angiogenin (ANG) Antibody
20-abx100299	Abbexa	EUR 425.00 EUR 133.00 EUR 1177.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Angiogenin (ANG) Antibody
20-abx100300	Abbexa	EUR 453.00 EUR 133.00 EUR 1288.00 EUR 620.00 EUR 342.00	100 ug 10 ug 1 mg 200 ug 50 ug

Angiogenin (ANG) Antibody
20-abx100301	Abbexa	EUR 453.00 EUR 133.00 EUR 1288.00 EUR 620.00 EUR 342.00	100 ug 10 ug 1 mg 200 ug 50 ug

Angiogenin (ANG) Antibody
20-abx100302	Abbexa	EUR 356.00 EUR 913.00 EUR 467.00 EUR 154.00 EUR 272.00	100 ug 1 mg 200 ug 20 ug 50 ug

Angiogenin (ANG) Antibody
20-abx001302	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Angiogenin (108-122)
5-00673	CHI Scientific	4 x 1mg	Ask for price

Angiogenin (108-123)
5-00674	CHI Scientific	4 x 1mg	Ask for price

Angiogenin (ANG) Antibody
20-abx171213	Abbexa	EUR 913.00 EUR 467.00	1 mg 200 ug

Angiogenin (ANG) Antibody
20-abx323491	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Angiogenin (ANG) Antibody
abx230390-100ug	Abbexa	100 ug	EUR 481

Angiogenin (ANG) Antibody
20-abx339590	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Angiogenin (ANG) Antibody
abx148162-100ug	Abbexa	100 ug	EUR 439

Angiogenin (ANG) Antibody
20-abx141176	Abbexa	EUR 356.00 EUR 537.00 EUR 217.00	100 ul 200 ul 30 ul

Angiogenin (ANG) Antibody
20-abx175378	Abbexa	EUR 1316.00 EUR 634.00	1 mg 200 ug

Angiogenin Polyclonal Antibody
42438-100ul	SAB	100ul	EUR 333

Recombinant Angiogenin (ANG)
4-RPA007Bo01	Cloud-Clone	EUR 504.99 EUR 238.00 EUR 1618.72 EUR 606.24 EUR 1112.48 EUR 401.00 EUR 3896.80	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Bovine Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)
4-RPA007Hu01	Cloud-Clone	EUR 458.40 EUR 226.00 EUR 1444.00 EUR 548.00 EUR 996.00 EUR 370.00 EUR 3460.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)
4-RPA007Mu01	Cloud-Clone	EUR 478.11 EUR 231.00 EUR 1517.92 EUR 572.64 EUR 1045.28 EUR 383.00 EUR 3644.80	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)
4-RPA007Mu02	Cloud-Clone	EUR 478.11 EUR 231.00 EUR 1517.92 EUR 572.64 EUR 1045.28 EUR 383.00 EUR 3644.80	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)
4-RPA007Po01	Cloud-Clone	EUR 530.08 EUR 245.00 EUR 1712.80 EUR 637.60 EUR 1175.20 EUR 418.00 EUR 4132.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Pig Angiogenin expressed in: E.coli

Recombinant Angiogenin (ANG)
4-RPA007Ra01	Cloud-Clone	EUR 485.28 EUR 233.00 EUR 1544.80 EUR 581.60 EUR 1063.20 EUR 388.00 EUR 3712.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Angiogenin expressed in: E.coli

Angiogenin (108-123)
H-8020.0001	Bachem	1.0mg	EUR 441
Description: Sum Formula: C83H132N26O24; CAS# [112173-48-5]

Angiogenin (108-123)
H-8020.0005	Bachem	5.0mg	EUR 1675
Description: Sum Formula: C83H132N26O24; CAS# [112173-48-5]

Angiogenin (108-122)
H-8095.0001	Bachem	1.0mg	EUR 212
Description: Sum Formula: C78H125N25O23; CAS# [112173-49-6]

Angiogenin (108-122)
H-8095.0005	Bachem	5.0mg	EUR 756
Description: Sum Formula: C78H125N25O23; CAS# [112173-49-6]

Angiogenin antibody (HRP)
60R-2121	Fitzgerald	100 ug	EUR 327
Description: Rabbit polyclonal Angiogenin antibody (HRP)

Angiogenin antibody (FITC)
60R-2122	Fitzgerald	100 ug	EUR 327
Description: Rabbit polyclonal Angiogenin antibody (FITC)

Angiogenin antibody (biotin)
60R-2123	Fitzgerald	100 ug	EUR 349
Description: Rabbit polyclonal Angiogenin antibody (biotin)

Angiogenin Recombinant Protein
91-183	ProSci	0.05 mg	EUR 464
Description: Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.

Human Angiogenin(ANG)ELISA Kit
GA-E1240HM-48T	GenAsia Biotech	48T	EUR 289

Human Angiogenin(ANG)ELISA Kit
GA-E1240HM-96T	GenAsia Biotech	96T	EUR 466

Human ANG/ Angiogenin ELISA Kit
E0142Hu	Sunlong	1 Kit	EUR 537

Human Angiogenin,ANG ELISA Kit
201-12-1224	SunredBio	96 tests	EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Angiogenin (ANG) CLIA Kit
20-abx490752	Abbexa	EUR 7378.00 EUR 3933.00 EUR 911.00	10 × 96 tests 5 × 96 tests 96 tests

Human Angiogenin (ANG) ELISA Kit
abx350014-96tests	Abbexa	96 tests	EUR 668

Human Angiogenin (ANG) ELISA Kit
20-abx150645	Abbexa	EUR 5640.00 EUR 3009.00 EUR 707.00	10 × 96 tests 5 × 96 tests 96 tests

Human Angiogenin (ANG) CLIA Kit
abx195094-96tests	Abbexa	96 tests	EUR 825

Human Angiogenin (ANG) ELISA Kit
RDR-RNASE5-Hu-48Tests	Reddot Biotech	48 Tests	EUR 383

Human Angiogenin (ANG) ELISA Kit
RDR-RNASE5-Hu-96Tests	Reddot Biotech	96 Tests	EUR 525

Human Angiogenin (ANG) ELISA Kit
RD-RNASE5-Hu-48Tests	Reddot Biotech	48 Tests	EUR 367

Human Angiogenin (ANG) ELISA Kit
RD-RNASE5-Hu-96Tests	Reddot Biotech	96 Tests	EUR 502

Human Angiogenin ELISA Kit (ANG)
RK00879	Abclonal	96 Tests	EUR 521

ELISA kit for Human Angiogenin
EK1015	SAB	96 tests	EUR 452
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Angiogenin in samples from serum, plasma, tissue homogenates and other biological fluids.

Human ANG(Angiogenin) ELISA Kit
EH0034	FN Test	96T	EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human Angiogenin (ANG) ELISA Kit
DLR-RNASE5-Hu-48T	DL Develop	48T	EUR 380
Description: A sandwich quantitative ELISA assay kit for detection of Human Angiogenin (ANG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Angiogenin (ANG) ELISA Kit
DLR-RNASE5-Hu-96T	DL Develop	96T	EUR 485
Description: A sandwich quantitative ELISA assay kit for detection of Human Angiogenin (ANG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Angiogenin (ANG) Polyclonal Antibody (Human)
4-PAA007Hu01	Cloud-Clone	EUR 194.00 EUR 1678.00 EUR 436.00 EUR 234.00 EUR 191.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Angiogenin (ANG)

Human Angiogenin, ANG ELISA Kit
CSB-E04498h-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitative sandwich ELISA kit for measuring Human Angiogenin, ANG in samples from serum, plasma, cell culture supernates, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Angiogenin, ANG ELISA Kit
1-CSB-E04498h	Cusabio	EUR 511.00 EUR 3491.00 EUR 1866.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Angiogenin, ANG in samples from serum, plasma, cell culture supernates, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Angiogenin (ANG) Monoclonal Antibody (Human)
4-MAA007Hu22	Cloud-Clone	EUR 249.00 EUR 2549.00 EUR 634.00 EUR 313.00 EUR 215.00	100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Angiogenin (ANG)

Human Angiogenin (ANG) ELISA Kit
SEA007Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 3409.41
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit
SEA007Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 368.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit
SEA007Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 483.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit
SEA007Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 1875.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Angiogenin (ANG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Angiogenin (ANG) ELISA Kit
4-SEA007Hu	Cloud-Clone	EUR 3460.00 EUR 1826.00 EUR 484.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Angiogenin (ANG) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Angiogenin(ANG)ELISA Kit
QY-E00700	Qayee Biotechnology	96T	EUR 361

Recombinant Human Angiogenin/ANG/RNASE5
C203-10ug	Novoprotein	10ug	EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Angiogenin/ANG/RNASE5
C203-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Angiogenin/ANG/RNASE5
C203-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Angiogenin/ANG/RNASE5
C203-50ug	Novoprotein	50ug	EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Human ANG / Angiogenin ELISA kit
LF-EK50621	Abfrontier	1×96T	EUR 648

Human Angiogenin,ANG ELISA Kit
CN-03157H1	ChemNorm	96T	EUR 378

Human Angiogenin,ANG ELISA Kit
CN-03157H2	ChemNorm	48T	EUR 289

Goat Anti-Human Angiogenin protein IgG #1, IgG aff pure
ANGN12-A	Alpha Diagnostics	100 ug	EUR 482

ELISA kit for Human ANG (Angiogenin)
ELK1830	ELK Biotech	1 plate of 96 wells	EUR 432
Description: A sandwich ELISA kit for detection of Angiogenin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.